Comparative Study of Attenuation of Cardiovascular Responses to Laryngoscopy and Intubation, Employing MgSO4 Vs Normal Saline - A Randomized Double Blinded Study

How to cite this article: Kiran Kumar H, Vijaya Kumar Ta. Comparative study of attenuation of cardiovascular responses to laryngoscopy and intubation, employing MgSO4 vs normal saline a randomized double blinded stud. International Journal of Contemporary Medical Research 2016;3(2):393-396. dial insufficiency6 and cerebrovascular accident.7 At least in such individuals there is a necessity to blunt these harmful hemodyamic effects. Many pharmacological methods have been devised to reduce the extent of hemodynamic events including high dose of opioids local anesthetics like lignocaine, alpha and beta adrenergic blockers and calcium channel blockers1 vasodilatation drugs like nitro glycerine.8 Topical anesthesia with lignocaine applied to the larynx and trachea in a variety of ways remains a popular method used alone or in combination with other techniques. Intravenous MgSO4 is a popular method of blunting this response, because of its ability to depress sympathoadrenal response and catacholamine release. Hence the present study was undertaken to compare the effect of Intravenous MgSO4 and intravenous normal saline as a placebo on blunting the haemodynamic responses to endotracheal intubation.